Empowering Innovation That Helps the World SMILE

SMILE Health is the accelerator program where transformational solutions to improve oral health take center stage.

We support innovators who challenge norms and are ready to advance solutions that improve accessibility, equity, and propel the integration between oral health and overall health.

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What Is SMILE Health?

CareQuest Innovation Partners and MATTER have joined together to launch SMILE Health for its third year. The 12-week semi-virtual program connects diverse innovators with a network of mission-aligned industry partners who help advance your solution and roadmap.

  • Non-Dilutive Cash Stipend: Receive a $10,000 stipend without giving up any equity.
  • Expert-Led Validation Studies: Tap into curated industry data and strengthen your business case.
  • 1:1 Mentorship: Connect with industry veterans who provide personalized guidance.
  • Custom Curriculum: Engage in immersive workshops tailored to health innovators.
  • Dedicated Pitch Support: Workshop pitches to present to medical and oral health leaders at a closed-door Reveal Day and Demo Day at HLTH 2024.
  • Ongoing Access: Gain a six-month MATTER membership upon program completion to continue building your business.
  • Future Growth: Apply for ACCELERATE, a program that provides incremental funding to collaborate with industry partners on mission-aligned projects.

Focus Areas

The 2024 SMILE Health accelerator program will focus on three primary areas of oral health innovation.

Advancing Accessible, Equitable, and Integrated Health

How can we make health care, including oral health, more accessible, equitable and/or integrated?

Reducing Disparities through Oral Health

How can we leverage innovative oral health solutions to better identify and/or address health disparities?

Connecting Chronic Care with Oral Health

How can we help people at risk or with chronic conditions better manage their overall health through oral health?

Who Should Apply?

We are calling for startups that have built a solution to improve oral health and care outcomes for all people and want to advance it with a mission-aligned community.

The SMILE Health program is open to global solutions across all disciplines, and applicants must:

  • Include an oral health focus or a potential use case to advance integrated health. The program has cross-industry representation and previous experience in oral health is not required.
  • Demonstrate a validated hypothesis or preliminary proof-of-concept of how your solution addresses our focus areas.
  • Commit to roughly 10-15 hours/week for 12 weeks by participating in mentor meetings, custom curriculum, and collaborative working sessions around validation.

Daniel Weinstein
CEO and Cofounder, Lura Health,
2023 SMILE Health cohort company

“[SMILE Health] is an ecosystem of partners all across the care continuum from insurance providers, payers, to dental manufacturers, to distributors, to care clinicians, and everybody in this community is really passionate about helping the companies here.”

About the Program

The key components of the SMILE Health program include:

Validation Studies

Data-driven validation studies driving key decisions and next steps including investments, pilots, and scale.

Mentorship & Curriculum

Access to multi-disciplinary expertise, mentorship, trainings, curated data, and other resources (during and after SMILE Health).


Meaningful opportunities to gain new insights, connections, and partners across broader health ecosystem.

Program Timeline

Applications are closed for 2024.

Our Industry Partners & Investors

We partner closely with mission-aligned industry partners and investors and are proud to have an extensive network of leaders eager to engage with you! In addition to CareQuest Innovation Partners and MATTER, industry partners will collaborate with you on your validation study by providing access to insights, networking, and additional resources. Investors will be engaged throughout SMILE Health, including mentorship and participation in Reveal and Demo Days. This is a unique opportunity to meaningfully engage with industry leaders and investors to catalyze outcomes during and after the accelerator program.

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About CareQuest Innovation Partners

CareQuest Innovation Partners validates and scales transformative solutions to improve overall health through oral health. Together, with our ecosystem of leading industry partners, startups, and investors we make care more accessible, equitable, and integrated. Joined by the shared mission to improve the oral health of all, CareQuest Innovation Partners is the for-profit subsidiary of CareQuest Institute.


At MATTER, we believe collaboration is the best way to improve healthcare. The MATTER collaborative includes more than 900 current and alumni startups from around the world, working together with dozens of hospitals and health systems, universities and industry-leading companies to build the future of healthcare. Together we are accelerating innovation, advancing care, and improving lives. For more information, visit matter.health and follow @MATTERhealth.

Together we can empower innovation that helps the world SMILE