Meet the SMILE Health Cohort


Chicago, Illinois

OrisDX Logo

OrisDX provides patients better clarity on their health through novel saliva-based diagnostics to identify pre-cancer and cancer. Based on innovative research from the University of Chicago, their first product detects oral cavity cancer through non-invasive genetic testing of patients’ saliva.

Denture Care Shop

Charleston, North Carolina

Denture Care Shop Logo

Denture Care Shop is disrupting a long overlooked and underserved segment of dentistry — dentures. Leveraging digital and 3D technology and new innovations in telemedicine, they aim to close a large accessibility gap and oral health crisis by offering a better, quicker and more affordable service.

Wide Awake VR

Ann Arbor, Michigan

WideAwake VR Logo

WAVR is a better and safer way for people to experience medical procedures without the need for sedatives. When patients use virtual reality (VR) to mitigate against anxiety, providers can use immersive media content instead of narcotics in the comfort and safety of their offices.


Newport Beach, California

SleepArchitects - Logo

SleepArchitects is democratizing access and integrating the full suite of sleep apnea options for dental professionals and consumers using a simple, convenient, turnkey digital experience. They offer automated text communication, patient education videos, full-service MD-guided home sleep testing and highly-trained dentists to offer a full suite of treatment options, making for happy and healthy patients and doctors.

Novel White Plastic Preformed Crown 

Dunedin, New Zealand

University of Otago - Logo

A research team out of New Zealand’s National Center for Dentistry at the University of Otago develops innovative dental products that will transform the international dental products market. Currently, they’re developing a novel, tooth-colored, preformed tooth crown for treating decayed teeth in children using the minimally invasive Hall Technique. They are academic researchers with extensive experience in dental biomaterials development, dental crown design, mechanical testing and clinical trials, working in collaboration with a polymer manufacturing company in New Zealand.